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Questioning regulation of two-pore channels by NAADP

NAADP is a potent Ca(2+) mobilizing messenger [1–3]. Since its discovery in 1995 [4] a considerable volume of literature has shown that NAADP couples cell stimulation to endolysosomal Ca(2+) release and thereby the regulation of many cellular functions [5]. However definition of its molecular mechan...

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Detalhes bibliográficos
Main Authors: Marchant, Jonathan S., Patel, Sandip
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018199/
https://ncbi.nlm.nih.gov/pubmed/24829847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/msr.2013.1027
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