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The Molecular Basis for Ca(2+) Signalling by NAADP: Two-Pore Channels in a Complex?

NAADP is a potent Ca(2+) mobilizing messenger in a variety of cells but its molecular mechanism of action is incompletely understood. Accumulating evidence indicates that the poorly characterized two-pore channels (TPCs) in animals are NAADP sensitive Ca(2+)-permeable channels. TPCs localize to the...

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Detalhes bibliográficos
Main Authors: Marchant, Jonathan S., Lin-Moshier, Yaping, Walseth, Timothy F., Patel, Sandip
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193953/
https://ncbi.nlm.nih.gov/pubmed/25309835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/msr.2012.1003
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