Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

Degradation rates of most proteins in eukaryotic cells are determined by their rates of ubiquitination. However, possible regulation of the proteasome's capacity to degrade ubiquitinated proteins has received little attention, although proteasome inhibitors are widely used in research and cance...

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Hlavní autoři: Besche, Henrike C, Sha, Zhe, Kukushkin, Nikolay V, Peth, Andreas, Hock, Eva-Maria, Kim, Woong, Gygi, Steven, Gutierrez, Juan A, Liao, Hua, Dick, Lawrence, Goldberg, Alfred L
Médium: Artigo
Jazyk:Inglês
Vydáno: BlackWell Publishing Ltd 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193922/
https://ncbi.nlm.nih.gov/pubmed/24811749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201386906
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