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Measuring the overall rate of protein breakdown in cells and the contributions of the ubiquitin-proteasome and autophagy-lysosomal pathways
In certain physiological or pathological states (e.g. starvation, heat shock, or muscle atrophy) and upon drug treatments, the overall rate of protein degradation in cells may increase or decrease. These adaptations and pathological responses can occur through alterations in substrate flux through t...
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| Опубликовано в: : | Methods Mol Biol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6441977/ https://ncbi.nlm.nih.gov/pubmed/30242715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8706-1_17 |
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