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Measuring the overall rate of protein breakdown in cells and the contributions of the ubiquitin-proteasome and autophagy-lysosomal pathways

In certain physiological or pathological states (e.g. starvation, heat shock, or muscle atrophy) and upon drug treatments, the overall rate of protein degradation in cells may increase or decrease. These adaptations and pathological responses can occur through alterations in substrate flux through t...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Sha, Zhe, Zhao, Jinghui, Goldberg, Alfred L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6441977/
https://ncbi.nlm.nih.gov/pubmed/30242715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8706-1_17
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