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Ca(2+)- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in lateral chain

Large conductance, calcium- and voltage-gated potassium (BK) channels regulate various physiological processes and represent an attractive target for drug discovery. Numerous BK channel activators are available. However, these agents usually interact with the ubiquitously distributed channel-forming...

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Main Authors: Bukiya, Anna N., Patil, Shivaputra, Li, Wei, Miller, Duane, Dopico, Alex M.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193543/
https://ncbi.nlm.nih.gov/pubmed/22945504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201200290
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