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Instability of the insertional mutation in Cftr(TgH(neoim)Hgu )cystic fibrosis mouse model

BACKGROUND: A major boost to the cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic strains facilitated the search for modif...

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Détails bibliographiques
Auteurs principaux: Charizopoulou, Nikoletta, Jansen, Silke, Dorsch, Martina, Stanke, Frauke, Dorin, Julia R, Hedrich, Hans-Jürgen, Tümmler, Burkhard
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC419339/
https://ncbi.nlm.nih.gov/pubmed/15102331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-5-6
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