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Instability of the insertional mutation in Cftr(TgH(neoim)Hgu )cystic fibrosis mouse model

BACKGROUND: A major boost to the cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic strains facilitated the search for modif...

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Detaylı Bibliyografya
Asıl Yazarlar: Charizopoulou, Nikoletta, Jansen, Silke, Dorsch, Martina, Stanke, Frauke, Dorin, Julia R, Hedrich, Hans-Jürgen, Tümmler, Burkhard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC419339/
https://ncbi.nlm.nih.gov/pubmed/15102331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-5-6
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