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Differential decay of parent-of-origin-specific genomic sharing in cystic fibrosis-affected sib pairs maps a paternally imprinted locus to 7q34

Cystic fibrosis (CF) is a monogenic disease characterized by a high variability of disease severity and outcome that points to the role of environmental factors and modulating genes that shape the course of this multiorgan disease. We genotyped families of cystic fibrosis sib pairs homozygous for F5...

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Detalhes bibliográficos
Main Authors: Stanke, Frauke, Davenport, Colin, Hedtfeld, Silke, Tümmler, Burkhard
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987319/
https://ncbi.nlm.nih.gov/pubmed/20051989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2009.229
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