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Direct-Acting Antiviral Agents for Hepatitis C Virus Infection

Two selective inhibitors of the hepatitis C virus (HCV) protease nearly double the cure rates for this infection when combined with peginterferon alfa and ribavirin. These drugs, boceprevir and telaprevir, received regulatory approval in 2011 and are the first direct-acting antiviral agents (DAAs) t...

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Autores principales: Kiser, Jennifer J., Flexner, Charles
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193385/
https://ncbi.nlm.nih.gov/pubmed/23140245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-011112-140254
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