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Direct-Acting Antiviral Agents for Hepatitis C Virus Infection

Two selective inhibitors of the hepatitis C virus (HCV) protease nearly double the cure rates for this infection when combined with peginterferon alfa and ribavirin. These drugs, boceprevir and telaprevir, received regulatory approval in 2011 and are the first direct-acting antiviral agents (DAAs) t...

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Bibliografische gegevens
Hoofdauteurs: Kiser, Jennifer J., Flexner, Charles
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193385/
https://ncbi.nlm.nih.gov/pubmed/23140245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-011112-140254
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