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Direct-Acting Antiviral Agents for Hepatitis C Virus Infection

Two selective inhibitors of the hepatitis C virus (HCV) protease nearly double the cure rates for this infection when combined with peginterferon alfa and ribavirin. These drugs, boceprevir and telaprevir, received regulatory approval in 2011 and are the first direct-acting antiviral agents (DAAs) t...

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Bibliografiske detaljer
Main Authors: Kiser, Jennifer J., Flexner, Charles
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193385/
https://ncbi.nlm.nih.gov/pubmed/23140245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-011112-140254
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