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Direct-Acting Antiviral Agents for Hepatitis C Virus Infection

Two selective inhibitors of the hepatitis C virus (HCV) protease nearly double the cure rates for this infection when combined with peginterferon alfa and ribavirin. These drugs, boceprevir and telaprevir, received regulatory approval in 2011 and are the first direct-acting antiviral agents (DAAs) t...

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Detalhes bibliográficos
Main Authors: Kiser, Jennifer J., Flexner, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4193385/
https://ncbi.nlm.nih.gov/pubmed/23140245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-011112-140254
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