Complement Alternative Pathway Activation in Human Nonalcoholic Steatohepatitis

The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH. However, it remained unclear whether the alternative pathway of complement, which amplifies C3 activation and which is frequently associat...

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Autores principales: Segers, Filip M., Verdam, Froukje J., de Jonge, Charlotte, Boonen, Bas, Driessen, Ann, Shiri-Sverdlov, Ronit, Bouvy, Nicole D., Greve, Jan Willem M., Buurman, Wim A., Rensen, Sander S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192551/
https://ncbi.nlm.nih.gov/pubmed/25299043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110053
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