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Complement Alternative Pathway Activation in Human Nonalcoholic Steatohepatitis

The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH. However, it remained unclear whether the alternative pathway of complement, which amplifies C3 activation and which is frequently associat...

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Dettagli Bibliografici
Autori principali: Segers, Filip M., Verdam, Froukje J., de Jonge, Charlotte, Boonen, Bas, Driessen, Ann, Shiri-Sverdlov, Ronit, Bouvy, Nicole D., Greve, Jan Willem M., Buurman, Wim A., Rensen, Sander S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192551/
https://ncbi.nlm.nih.gov/pubmed/25299043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110053
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