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Complement Alternative Pathway Activation in Human Nonalcoholic Steatohepatitis

The innate immune system plays a major role in the pathogenesis of nonalcoholic steatohepatitis (NASH). Recently we reported complement activation in human NASH. However, it remained unclear whether the alternative pathway of complement, which amplifies C3 activation and which is frequently associat...

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Bibliografische gegevens
Hoofdauteurs: Segers, Filip M., Verdam, Froukje J., de Jonge, Charlotte, Boonen, Bas, Driessen, Ann, Shiri-Sverdlov, Ronit, Bouvy, Nicole D., Greve, Jan Willem M., Buurman, Wim A., Rensen, Sander S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192551/
https://ncbi.nlm.nih.gov/pubmed/25299043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110053
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