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Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference Processing
The enzyme Dicer generates 21–25 nucleotide RNAs that target specific mRNAs for silencing during RNA interference and related pathways. Although their active sites and RNA binding regions are functionally conserved, the helicase domains have distinct activities in the context of different Dicer enzy...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4192488/ https://ncbi.nlm.nih.gov/pubmed/25135636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589051 |
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