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Synthesis and Characterization of Valyloxy Methoxy Luciferin for the Detection of Valacyclovirase and Peptide Transporter

[Image: see text] An amino acid ester derivative of luciferin (valoluc) was synthesized to mimic the transport and activation of valacyclovir. This molecule was characterized in vitro for specificity and enzymatic constants, and then assayed in two different, physiologically-relevant conditions. It...

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Autors principals: Walls, Zachary F., Gupta, Sheeba Varghese, Amidon, Gordon L., Lee, Kyung-Dall
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192071/
https://ncbi.nlm.nih.gov/pubmed/25240255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.09.011
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