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Chemical and Enzymatic Stability of Amino acid Prodrugs Containing Methoxy, Ethoxy and Propylene Glycol Linkers
PURPOSE: To evaluate the chemical and enzymatic stabilities of methoxy, ethoxy and propylene glycol linker containing prodrugs in order to find a suitable linker for prodrugs of carboxylic acids with amino acids. METHODS: L-valine and L-phenylalanine prodrugs of model compounds (benzoic acid and phe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496387/ https://ncbi.nlm.nih.gov/pubmed/19566080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900084v |
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