A Novel Multivalent, Single-Domain Antibody Targeting TcdA and TcdB Prevents Fulminant Clostridium difficile Infection in Mice

The incidence of Clostridium difficile infection (CDI) and associated mortality have increased rapidly worldwide in recent years. Therefore, it is critical to develop new therapies for CDI. In this study, we generated a novel, potently neutralizing, tetravalent, and bispecific antibody composed of 2...

詳細記述

保存先:
書誌詳細
主要な著者: Yang, Zhiyong, Schmidt, Diane, Liu, Weilong, Li, Shan, Shi, Lianfa, Sheng, Jinliang, Chen, Kevin, Yu, Hua, Tremblay, Jacqueline M., Chen, Xinhua, Piepenbrink, Kurt H., Sundberg, Eric J., Kelly, Ciaran P., Bai, Guang, Shoemaker, Charles B., Feng, Hanping
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2014
主題:
Major Articles and Brief Reports
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4192054/
https://ncbi.nlm.nih.gov/pubmed/24683195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu196
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料