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Stereocontrolled Synthesis of Syn-β-Hydroxy-α-Amino Acids by Direct Aldolization of Pseudoephenamine Glycinamide
β-Hydroxy-α-amino acids figure prominently as chiral building blocks in chemical synthesis, serving as precursors to numerous important medicines. We have developed and here report a method for the synthesis of β-hydroxy-α-amino acid derivatives by aldolization of pseudoephenamine glycinamide, which...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191905/ https://ncbi.nlm.nih.gov/pubmed/24692320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201400928 |
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