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Expedient Synthesis of syn-β-Hydroxy-α-amino acid derivatives: Phenylalanine, Tyrosine, Histidine and Tryptophan

An expedient synthesis of enantiomerically pure threo-β-hydroxy-α-amino acid derivatives of phenylalanine, tyrosine, histidine and tryptophan is described. The NBS-mediated radical bromination of the N,N-di-tert-butoxycarbonyl protected α-amino acids and subsequent treatment with silver nitrate in a...

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Detalhes bibliográficos
Main Authors: Crich, David, Banerjee, Abhisek
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621330/
https://ncbi.nlm.nih.gov/pubmed/16930077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo061159i
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