Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling

Folding of the chromosomal fibre in interphase nuclei is an important element in the regulation of gene expression. For instance, physical contacts between promoters and enhancers are a key element in cell-type–specific transcription. We know remarkably little about the principles that control chrom...

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Detaylı Bibliyografya
Asıl Yazarlar: Tark-Dame, Mariliis, Jerabek, Hansjoerg, Manders, Erik M. M., Heermann, Dieter W., van Driel, Roel
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191888/
https://ncbi.nlm.nih.gov/pubmed/25299688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003877
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