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Depletion Effects Massively Change Chromatin Properties and Influence Genome Folding
We present a Monte Carlo model for genome folding at the 30-nm scale with focus on linker-histone and nucleosome depletion effects. We find that parameter distributions from experimental data do not lead to one specific chromatin fiber structure, but instead to a distribution of structures in the ch...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2764066/ https://ncbi.nlm.nih.gov/pubmed/19843447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.06.057 |
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