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Localization Microscopy Reveals Expression-Dependent Parameters of Chromatin Nanostructure

A combined approach of 2D high-resolution localization light microscopy and statistical methods is presented to infer structural features and density fluctuations at the nuclear nanoscale. Hallmarks of nuclear nanostructure are found on the scale below 100 nm for both human fibroblast and HeLa cells...

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Bibliographic Details
Main Authors: Bohn, Manfred, Diesinger, Philipp, Kaufmann, Rainer, Weiland, Yanina, Müller, Patrick, Gunkel, Manuel, von Ketteler, Alexa, Lemmer, Paul, Hausmann, Michael, Heermann, Dieter W., Cremer, Christoph
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931727/
https://ncbi.nlm.nih.gov/pubmed/20816047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.05.043
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