Engagement of myelomonocytic Siglecs by tumor-associated ligands modulates the innate immune response to cancer

Certain pathogenic bacteria are known to modulate the innate immune response by decorating themselves with sialic acids, which can engage the myelomonocytic lineage inhibitory receptor Siglec-9, thereby evading immunosurveillance. We hypothesized that the well-known up-regulation of sialoglycoconjug...

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Bibliografische gegevens
Hoofdauteurs: Läubli, Heinz, Pearce, Oliver M. T., Schwarz, Flavio, Siddiqui, Shoib S., Deng, Lingquan, Stanczak, Michal A., Deng, Liwen, Verhagen, Andrea, Secrest, Patrick, Lusk, Chrissy, Schwartz, Ann G., Varki, Nissi M., Bui, Jack D., Varki, Ajit
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191788/
https://ncbi.nlm.nih.gov/pubmed/25225409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409580111
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