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Sialic acid–binding immunoglobulin-like lectins (Siglecs) detect self-associated molecular patterns to regulate immune responses
The mammalian immune system evolved to tightly regulate the elimination of pathogenic microbes and neoplastic transformed cells while tolerating our own healthy cells. Here, we summarize experimental evidence for the role of Siglecs—in particular CD33-related Siglecs—as self-receptors and their sial...
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| Published in: | Cell Mol Life Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer International Publishing
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7942692/ https://ncbi.nlm.nih.gov/pubmed/31485715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03288-x |
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