Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells

First-generation immune checkpoint inhibitors, including anti–CTLA-4 and anti–programmed death 1 (anti–PD-1) antibodies, have led to major clinical progress, yet resistance frequently leads to treatment failure. Thus, new targets acting on T cells are needed. CD33-related sialic acid–binding immunog...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Clin Invest
मुख्य लेखकों: Stanczak, Michal A., Siddiqui, Shoib S., Trefny, Marcel P., Thommen, Daniela S., Boligan, Kayluz Frias, von Gunten, Stephan, Tzankov, Alexandar, Tietze, Lothar, Lardinois, Didier, Heinzelmann-Schwarz, Viola, von Bergwelt-Baildon, Michael, Zhang, Wu, Lenz, Heinz-Josef, Han, Younghun, Amos, Christopher I., Syedbasha, Mohammedyaseen, Egli, Adrian, Stenner, Frank, Speiser, Daniel E., Varki, Ajit, Zippelius, Alfred, Läubli, Heinz
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205408/
https://ncbi.nlm.nih.gov/pubmed/30130255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI120612
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