Lectin Galactoside-binding Soluble 3 Binding Protein (LGALS3BP) Is a Tumor-associated Immunomodulatory Ligand for CD33-related Siglecs

Lectin galactoside-binding soluble 3 binding protein (LGALS3BP, also called Mac-2 binding protein) is a heavily glycosylated secreted molecule that has been shown previously to be up-regulated in many cancers and has been implicated in tumor metastatic processes, as well as in other cell adhesion an...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Läubli, Heinz, Alisson-Silva, Frederico, Stanczak, Michal A., Siddiqui, Shoib S., Deng, Liwen, Verhagen, Andrea, Varki, Nissi, Varki, Ajit
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246102/
https://ncbi.nlm.nih.gov/pubmed/25320078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.593129
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