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Dynamics of RNA modification by a multi-site-specific tRNA methyltransferase
In most organisms, the widely conserved 1-methyl-adenosine58 (m(1)A(58)) tRNA modification is catalyzed by an S-adenosyl-L-methionine (SAM)-dependent, site-specific enzyme TrmI. In archaea, TrmI also methylates the adjacent adenine 57, m(1)A(57) being an obligatory intermediate of 1-methyl-inosine57...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191401/ https://ncbi.nlm.nih.gov/pubmed/25217588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku820 |
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