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Structural comparison of tRNA m(1)A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions

BACKGROUND: tRNA m(1)A58 methyltransferases (TrmI) catalyze the transfer of a methyl group from S-adenosyl-L-methionine to nitrogen 1 of adenine 58 in the T-loop of tRNAs from all three domains of life. The m(1)A58 modification has been shown to be essential for cell growth in yeast and for adaptati...

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Detalhes bibliográficos
Main Authors: Guelorget, Amandine, Barraud, Pierre, Tisné, Carine, Golinelli-Pimpaneau, Béatrice
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281791/
https://ncbi.nlm.nih.gov/pubmed/22168821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-11-48
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