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Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m(1)A57/58 methyltransferase
The S-adenosyl-l-methionine dependent methylation of adenine 58 in the T-loop of tRNAs is essential for cell growth in yeast or for adaptation to high temperatures in thermophilic organisms. In contrast to bacterial and eukaryotic tRNA m(1)A58 methyltransferases that are site-specific, the homologou...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952851/ https://ncbi.nlm.nih.gov/pubmed/20483913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq381 |
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