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Topological constraints are major determinants of tRNA tertiary structure and dynamics and provide basis for tertiary folding cooperativity

Recent studies have shown that basic steric and connectivity constraints encoded at the secondary structure level are key determinants of 3D structure and dynamics in simple two-way RNA junctions. However, the role of these topological constraints in higher order RNA junctions remains poorly underst...

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Detalhes bibliográficos
Main Authors: Mustoe, Anthony M., Brooks, Charles L., Al-Hashimi, Hashim M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191394/
https://ncbi.nlm.nih.gov/pubmed/25217593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku807
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