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Topological constraints are major determinants of tRNA tertiary structure and dynamics and provide basis for tertiary folding cooperativity

Recent studies have shown that basic steric and connectivity constraints encoded at the secondary structure level are key determinants of 3D structure and dynamics in simple two-way RNA junctions. However, the role of these topological constraints in higher order RNA junctions remains poorly underst...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mustoe, Anthony M., Brooks, Charles L., Al-Hashimi, Hashim M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191394/
https://ncbi.nlm.nih.gov/pubmed/25217593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku807
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