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Single-molecule analysis uncovers the difference between the kinetics of DNA decatenation by bacterial topoisomerases I and III

Escherichia coli topoisomerases I and III can decatenate double-stranded DNA (dsDNA) molecules containing single-stranded DNA regions or nicks as well as relax negatively supercoiled DNA. Although the proteins share a mechanism of action and have similar structures, they participate in different cel...

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Autori principali: Terekhova, Ksenia, Marko, John F., Mondragón, Alfonso
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191389/
https://ncbi.nlm.nih.gov/pubmed/25232096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku785
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