miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways

Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Glioma-initiating cells (GICs) are stem-like cells that have been implicated in glioblastoma progression and recurrence; however, the distinct properties of GICs and non-GICs within GBM tumors are largely uncharacterized. Here,...

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Detalhes bibliográficos
Main Authors: Wang, Hui, Sun, Tao, Hu, Jing, Zhang, Rui, Rao, Yanhua, Wang, Shuai, Chen, Rui, McLendon, Roger E., Friedman, Allan H., Keir, Stephen T., Bigner, Darell D., Li, Qi-Jing, Wang, Huibo, Wang, Xiao-Fan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191031/
https://ncbi.nlm.nih.gov/pubmed/25202981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75284
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