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miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways
Glioblastoma (GBM) is the most common and lethal brain tumor in adults. Glioma-initiating cells (GICs) are stem-like cells that have been implicated in glioblastoma progression and recurrence; however, the distinct properties of GICs and non-GICs within GBM tumors are largely uncharacterized. Here,...
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| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191031/ https://ncbi.nlm.nih.gov/pubmed/25202981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75284 |
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