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CD4(+) and CD8(+) T cell–dependent antiviral immunity requires STIM1 and STIM2
Calcium signaling is critical for lymphocyte function, and intracellular Ca(2+) concentrations are regulated by store-operated Ca(2+) entry (SOCE) through Ca(2+) release–activated Ca(2+) (CRAC) channels. In patients, loss-of-function mutations in CRAC channel components ORAI1 and STIM1 abolish SOCE...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191007/ https://ncbi.nlm.nih.gov/pubmed/25157823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76602 |
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