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The epigenetics of epithelial-mesenchymal plasticity in cancer

During the course of malignant cancer progression, neoplastic cells undergo dynamic and reversible transitions between multiple phenotypic states, the extremes of which are defined by the expression of epithelial and mesenchymal phenotypes. This plasticity is enabled by underlying shifts in epigenet...

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Detalhes bibliográficos
Main Authors: Tam, Wai Leong, Weinberg, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190672/
https://ncbi.nlm.nih.gov/pubmed/24202396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3336
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