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The epigenetics of epithelial-mesenchymal plasticity in cancer

During the course of malignant cancer progression, neoplastic cells undergo dynamic and reversible transitions between multiple phenotypic states, the extremes of which are defined by the expression of epithelial and mesenchymal phenotypes. This plasticity is enabled by underlying shifts in epigenet...

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Main Authors: Tam, Wai Leong, Weinberg, Robert A
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190672/
https://ncbi.nlm.nih.gov/pubmed/24202396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3336
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