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Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer

Tumor metastasis is the major cause of mortality and morbidity in most solid cancers. A growing body of evidence suggests that the epithelial-to-mesenchymal transition (EMT) plays a central role during tumor metastasis and frequently imparts a stem cell-like phenotype and therapeutic resistance to t...

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Autors principals: Bedi, Upasana, Mishra, Vivek Kumar, Wasilewski, David, Scheel, Christina, Johnsen, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039141/
https://ncbi.nlm.nih.gov/pubmed/24840099
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