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The epigenetics of epithelial-mesenchymal plasticity in cancer

During the course of malignant cancer progression, neoplastic cells undergo dynamic and reversible transitions between multiple phenotypic states, the extremes of which are defined by the expression of epithelial and mesenchymal phenotypes. This plasticity is enabled by underlying shifts in epigenet...

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Dettagli Bibliografici
Autori principali: Tam, Wai Leong, Weinberg, Robert A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190672/
https://ncbi.nlm.nih.gov/pubmed/24202396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3336
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