Mapping Membrane Protein Backbone Dynamics: A Comparison of Site-Directed Spin Labeling with NMR (15)N-Relaxation Measurements

The ability to detect nanosecond backbone dynamics with site-directed spin labeling (SDSL) in soluble proteins has been well established. However, for membrane proteins, the nitroxide appears to have more interactions with the protein surface, potentially hindering the sensitivity to backbone motion...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Lo, Ryan H., Kroncke, Brett M., Solomon, Tsega L., Columbus, Linda
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Biophysical Society 2014
Ämnen:
Proteins and Nucleic Acids
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190660/
https://ncbi.nlm.nih.gov/pubmed/25296323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.08.018
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk