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Extensive backbone dynamics in the GCAA RNA tetraloop analyzed using (13)C NMR spin relaxation and specific isotope labeling
Conformational dynamics play a key role in the properties and functions of proteins and nucleic acids. Heteronuclear NMR spin relaxation is a uniquely powerful site-specific probe of dynamics in proteins and has found increasing applications to nucleotide base side chains and anomeric sites in RNA....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729180/ https://ncbi.nlm.nih.gov/pubmed/19049467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805759z |
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