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Identification and removal of nitroxide spin label contaminant: Impact on PRE studies of α-helical membrane proteins in detergent

NMR paramagnetic relaxation enhancement (PRE) provides long-range distance constraints (∼15–25 Å) that can be critical to determining overall protein topology, especially where long-range NOE information is unavailable such as in the case of larger proteins that require deuteration. However, several...

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Détails bibliographiques
Auteurs principaux: Kroncke, Brett M, Columbus, Linda
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375759/
https://ncbi.nlm.nih.gov/pubmed/22389096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2038
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