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Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling

BACKGROUND: Luminal, estrogen receptor-positive breast cancers represent more than 70% of cases. Despite initial good prognoses one third of Luminal cancers eventually recur locally or at distant sites and exhibit hormone resistance. Here we demonstrate that factors elaborated by malignant stromal c...

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Detalhes bibliográficos
Main Authors: Pinto, Mauricio P, Dye, Wendy W, Jacobsen, Britta M, Horwitz, Kathryn B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190420/
https://ncbi.nlm.nih.gov/pubmed/25274034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-735
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