Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells

INTRODUCTION: Luminal, estrogen receptor-positive (ER(+)) breast cancers can metastasize but lie dormant for years before recurrences prove lethal. Understanding the roles of estrogen (E) or progestin (P) in development of luminal metastases or in arousal from dormancy is hindered by few preclinical...

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Опубликовано в: :Breast Cancer Res
Главные авторы: Ogba, Ndiya, Manning, Nicole G, Bliesner, Brian S, Ambler, S Kelly, Haughian, James M, Pinto, Mauricio P, Jedlicka, Paul, Joensuu, Kristiina, Heikkilä, Päivi, Horwitz, Kathryn B
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303198/
https://ncbi.nlm.nih.gov/pubmed/25475897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0489-4
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