Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells

INTRODUCTION: Luminal, estrogen receptor-positive (ER(+)) breast cancers can metastasize but lie dormant for years before recurrences prove lethal. Understanding the roles of estrogen (E) or progestin (P) in development of luminal metastases or in arousal from dormancy is hindered by few preclinical...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Ogba, Ndiya, Manning, Nicole G, Bliesner, Brian S, Ambler, S Kelly, Haughian, James M, Pinto, Mauricio P, Jedlicka, Paul, Joensuu, Kristiina, Heikkilä, Päivi, Horwitz, Kathryn B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303198/
https://ncbi.nlm.nih.gov/pubmed/25475897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0489-4
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