Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease

INTRODUCTION: Many Luminal breast cancers are heterogeneous, containing substantial numbers of estrogen (ER) and progesterone (PR) receptor-negative cells among the ER+ PR+ ones. One such subpopulation we call “Luminobasal” is ER-, PR- and cytokeratin 5 (CK5)-positive. It is not targeted for treatme...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Knox, Aaron J, Scaling, Allison L, Pinto, Mauricio P, Bliesner, Brian S, Haughian, James M, Abdel-Hafiz, Hany A, Horwitz, Kathryn B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187339/
https://ncbi.nlm.nih.gov/pubmed/25116921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-014-0418-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados