Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch

Luminal breast cancers express estrogen (ER) and/or progesterone (PR) receptors and respond to hormone therapies. Basal-like “triple negative” cancers lack steroid receptors but are cytokeratin (CK) 5-positive and require chemotherapy. Here we show that more than half of primary ER(+)PR(+) breast ca...

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Main Authors: Haughian, James M., Pinto, Mauricio P., Harrell, J. Chuck, Bliesner, Brian S., Joensuu, Kristiina M., Dye, Wendy W., Sartorius, Carol A., Tan, Aik Choon, Heikkilä, Päivi, Perou, Charles M., Horwitz, Kathryn B.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
Assuntos:
Breast Cancer Special Feature
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287001/
https://ncbi.nlm.nih.gov/pubmed/21969591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106509108
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