Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone independent growth of estrogen receptor positive breast cancer

“Reactive” or activated stroma characterizes many malignancies including breast cancers. Recently we isolated a reactive mouse mammary gland stromal cell line called BJ3Z (1). These cells express α-smooth muscle actin (α-SMA) and stromal-cell derived factor 1 (SDF-1), and are tumorigenic when inject...

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Hauptverfasser: Pinto, Mauricio P., Badtke, Melanie M., Dudevoir, Michelle L., Harrell, J. Chuck, Jacobsen, Britta M., Horwitz, Kathryn B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848872/
https://ncbi.nlm.nih.gov/pubmed/20332242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4373
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