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Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone independent growth of estrogen receptor positive breast cancer

“Reactive” or activated stroma characterizes many malignancies including breast cancers. Recently we isolated a reactive mouse mammary gland stromal cell line called BJ3Z (1). These cells express α-smooth muscle actin (α-SMA) and stromal-cell derived factor 1 (SDF-1), and are tumorigenic when inject...

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Detalhes bibliográficos
Main Authors: Pinto, Mauricio P., Badtke, Melanie M., Dudevoir, Michelle L., Harrell, J. Chuck, Jacobsen, Britta M., Horwitz, Kathryn B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2848872/
https://ncbi.nlm.nih.gov/pubmed/20332242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4373
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