Early immune adaptation in HIV-1 revealed by population-level approaches

BACKGROUND: The reproducible nature of HIV-1 escape from HLA-restricted CD8+ T-cell responses allows the identification of HLA-associated viral polymorphisms “at the population level” – that is, via analysis of cross-sectional, linked HLA/HIV-1 genotypes by statistical association. However, elucidat...

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Main Authors: Martin, Eric, Carlson, Jonathan M, Le, Anh Q, Chopera, Denis R, McGovern, Rachel, Rahman, Manal A, Ng, Carmond, Jessen, Heiko, Kelleher, Anthony D, Markowitz, Martin, Allen, Todd M, Milloy, M-J, Carrington, Mary, Wainberg, Mark A, Brumme, Zabrina L
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190299/
https://ncbi.nlm.nih.gov/pubmed/25212686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0064-1
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